Abstract:
Objective To investigate the sleep quality of biosafety laboratory(BSL) personnel in Xinjiang and assess the impact of shift work and job burnout on sleep quality.
Methods In July 2022, an electronic questionnaire survey was conducted among 1 980 BSL personnel across Xinjiang. Job burnout was assessed using the MBI-General Survey(MBIGS), while sleep quality was evaluated using the Pittsburgh Sleep Quality Index(PSQI). Multivariate logistic regression analysis was employed to identify factors influencing sleep quality, with adjustments for confounding variables. The interactive effects of shift work and job burnout on sleep quality were analyzed by calculation of excess relative risk, interaction index, and attributable proportion.
Results A total of 1 591 valid questionnaires were collected, with a valid response rate of 80.35%. The median(25th and 75th percentiles) of the overall sleep quality score were 6.00 (4.00, 9.00) points. Logistic regression analysis showed that the risk of sleep disorders was reduced for BSL personnel with intermediate professional titles relative to those with junior titles(OR = 0.70, P < 0.05). Compared with workers aged < 30 years, those aged 30 to 39, 40 to 49, and ≥ 50 years were more likely to experience sleep disorders(OR = 1.56, 1.87, 2.86, all P < 0.01). Shift workers had a higher risk of sleep disorders than those who worked regular day shifts (OR = 1.18, P < 0.01). Workers with job burnout were more prone to sleep disorders compared to those without burnout(OR = 3.09, P < 0.01). After adjusting for confounding factors (age, gender, education level, professional title, marital status, personal monthly income, and shift patterns), multivariate logistic regression analysis showed that the risk of poor sleep quality was 4.09 times higher(95%CI: 2.71 to 6.17) in BSL personnel experiencing both job burnout and shift work than in those with neither. The interaction excess relative risk, interaction index, and attributable proportion were 2.07(95%CI: 1.10 to 3.05), 2.74 (95%CI: 1.32 to 5.69), and 48.6%(95%CI: 30.90% to 66.30%), respectively.
Conclusions There was a synergistic interaction between job burnout and shift work in influencing the sleep quality of BSL personnel. The coexistence of job burnout and shift work significantly increased the risk of sleep disorders.