刁军, 唐凤, 杨敏, 牟娜, 罗禹. 1954—2022 年重庆市九龙坡区尘肺病报告病例特征及生存分析[J]. 职业卫生与应急救援, 2025, 43(4): 465-470. DOI: 10.16369/j.oher.issn.1007-1326.2025.240658
引用本文: 刁军, 唐凤, 杨敏, 牟娜, 罗禹. 1954—2022 年重庆市九龙坡区尘肺病报告病例特征及生存分析[J]. 职业卫生与应急救援, 2025, 43(4): 465-470. DOI: 10.16369/j.oher.issn.1007-1326.2025.240658
DIAO Jun, TANG Feng, YANG Min, MOU Na, LUO Yu. Characteristics and survival analysis of pneumoconiosis cases reported in Jiulongpo District, Chongqing, from 1954 to 2022[J]. Occupational Health and Emergency Rescue, 2025, 43(4): 465-470. DOI: 10.16369/j.oher.issn.1007-1326.2025.240658
Citation: DIAO Jun, TANG Feng, YANG Min, MOU Na, LUO Yu. Characteristics and survival analysis of pneumoconiosis cases reported in Jiulongpo District, Chongqing, from 1954 to 2022[J]. Occupational Health and Emergency Rescue, 2025, 43(4): 465-470. DOI: 10.16369/j.oher.issn.1007-1326.2025.240658

1954—2022 年重庆市九龙坡区尘肺病报告病例特征及生存分析

Characteristics and survival analysis of pneumoconiosis cases reported in Jiulongpo District, Chongqing, from 1954 to 2022

  • 摘要:
    目的 掌握重庆市九龙坡区尘肺病报告病例的发病特征及生存状况,为当地尘肺病防治提供科学依据。
    方法 以重庆市九龙坡区截至2022年底报告的所有职业性尘肺病患者为调查对象,开展回顾性调查;对截至2019年调查时仍存活的尘肺病患者511例和2019年以后12例新报告的尘肺病患者共计523例进行电话随访,随访时间截至2023年底。对尘肺病患者的性别、年龄、工龄和尘肺种类以及首诊年龄等进行描述性统计学分析。采用Kaplan-Meier生存曲线和Cox回归模型对随访患者进行生存分析。
    结果 1954—2022年,重庆市九龙坡区共诊断1 142例职业性尘肺病例,主要为矽肺和煤工尘肺,共占98.4%。初期诊断壹期尘肺病673例(占58.93%)、贰期尘肺病295例(占25.83%),叁期尘肺病174例(占15.24%)。481例有完整信息的患者最终纳入生存分析,其中包括387例存活患者、2020—2023年随访期间死于尘肺病及其并发症的患者61例,以及33例失访及其他死因患者。Kaplan-Meier分析显示,481例尘肺病患者诊断后中位生存期为39.75年。Cox回归模型分析结果显示:首诊年龄≥ 55岁组的生存时间减少的风险是 < 45岁组的7.524倍(P<0.01),叁期尘肺病患者的生存时间减少的风险是壹期的2.154倍(P<0.05);尘肺病患者的工伤保险保障、尘肺类型和接尘工龄对患者生存时间没有影响(P > 0.05)。
    结论 尘肺病患者的生存时间同首诊年龄和尘肺病期别有关。早期诊断和防止尘肺病的恶化对于改善患者生存时间至关重要。应将首次诊断年龄较大和尘肺病叁期的患者作为重点人群进行随访监测,提高其生活质量,延长患者寿命。

     

    Abstract:
    Objective To investigate the epidemiological characteristics and survival status of pneumoconiosis cases reported in Jiulongpo District, Chongqing, and to provide scientific evidence for prevention and control strategies.
    Methods A retrospective study was conducted on all cases of occupational pneumoconiosis reported in Jiulongpo District up to the end of 2022. The telephone follow-up was conducted on 523 patients, including 511 cases who were still alive at the time of a 2019 survey and 12 new cases reported after 2019. The follow-up period lasted until the end of 2023. Descriptive statistics were used to analyze gender, age, dust exposure duration, type of pneumoconiosis, and age at first diagnosis. Survival analysis was performed using Kaplan-Meier curves and the Cox proportional hazards model.
    Results From 1954 to 2022, a total of 1 142 cases of occupational pneumoconiosis were diagnosed in Jiulongpo District, Chongqing, with silicosis and coal workers' pneumoconiosis accounting for 98.4% of the cases. Among them, 673 cases (58.93%) were diagnosed as stage Ⅰ, 295 cases (25.83%) as stage Ⅱ, and 174 cases (15.24%) as stage Ⅲ pneumoconiosis. A total of 481 cases with complete information were included in the survival analysis, comprising 387 surviving patients, 61 patients who died from pneumoconiosis or its complications between 2020 and 2023, and 33 patients who were lost to follow-up or died from other causes. Kaplan-Meier analysis showed that a median survival time after diagnosis for the 481 pneumoconiosis patients was 39.75 years. The Cox regression model revealed that patients first diagnosed at age ≥ 55 had a 7.524 times higher risk of reduced survival compared to those diagnosed at age < 45 (P < 0.01). Stage Ⅲ pneumoconiosis patients had a 2.154 times higher risk of reduced survival compared to stage Ⅰ patients (P < 0.05). Work-related injury insurance coverage, type of pneumoconiosis, and dust exposure duration had no significant effect on survival time (P > 0.05).
    Conclusions Survival time among pneumoconiosis patients was associated with age at first diagnosis and disease stage. Early diagnosis and prevention of disease progression were critical for improving patient survival time. Priority follow-up and monitoring should target patients diagnosed at older ages and those with stage Ⅲ pneumoconiosis to improve quality of life and extend longevity.

     

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