Objective To explore the clinical efficacy of Bufei Huoxue capsule combined with Tendon warm acupuncture and spectral instrument in the treatment of stage Ⅰ silicosis with blood stasis, to provide new guidance for treatment of traditional Chinese medicine in silicosis with blood stasis.
Methods Totally 104 patients diagnosed as Stage I silicosis with blood stasis were randomized into traditional treatment group and comprehensive treatment group. Except for the oxygen therapy, diet regulation and basic treatment in both groups, the patients in the traditional group were treated with tetrandrine tablets and the patients in comprehensive group were treated with Bufei Huoxue capsule combined with Tendon warm acupuncture and spectral therapy for 40 days. After treatment for 7 months, the patients in both groups were examined and the indicators were compared.
Results The St. George's respiratory questionnaire showed that the patients in comprehensive group had less respiratory symptoms, better activity ability and less effects of disease on daily life than the patients in traditional group(P < 0.01). There was no significant difference in the positive rate of anxiety between the two groups after treatmen(t P > 0.05). After treatment, the vital capacity and one second rate of patients in the comprehensive group were higher than those of the patients in traditional group (P < 0.05);there was no obvious abnormality of safety in both groups.
Conclusions Bufei Huoxue capsule combined with Tendon warm acupuncture and spectral therapy had advantages in the treatment of stage I silicosis with blood stasis, which could improve the patients' respiratory muscle fatigue, lung expansion ability, respiratory symptoms, activity ability and the influence of disease on daily life. It is worthy of further study and application in the clinic.
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